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A retrospective examination of the US Food and Drug Administration’s clinical pharmacology reviews of oncology biologics for potential use of therapeutic drug monitoring

BACKGROUND: Biologics have gained traction for use in oncology, but have demonstrate clinical variability for efficacy and safety. Therapeutic drug monitoring (TDM) can benefit patients’ outcomes from a biologic therapy when the latter has a defined therapeutic window. A clinically relevant therapeu...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Autores principales: Fleisher, Brett, Ait-Oudhia, Sihem
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749565/
https://ncbi.nlm.nih.gov/pubmed/29343970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S153056
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