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Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines

PURPOSE: Anastrozole (ANS) is an aromatase inhibitor that is widely used as a treatment for breast cancer in postmenopausal women. Despite the wide use of ANS, it is associated with serious side effects due to uncontrolled delivery. In addition, ANS exhibits low solubility and short plasma half-life...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Alyafee, Yusra A, Alaamery, Manal, Bawazeer, Shahad, Almutairi, Mansour S, Alghamdi, Badr, Alomran, Nawaf, Sheereen, Atia, Daghestani, Maha, Massadeh, Salam
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749378/
https://ncbi.nlm.nih.gov/pubmed/29343958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S151139
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