Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease

OBJECTIVE: An inadequate host response to the intestinal microbiota likely contributes to the manifestation and progression of human inflammatory bowel disease (IBD). However, molecular approaches to unravelling the nature of the defective crosstalk and its consequences for intestinal metabolic and...

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Veröffentlicht in:Gut
Hauptverfasser: Häsler, Robert, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Barann, Matthias, Rehman, Ateequr, Esser, Daniela, Aden, Konrad, Knecht, Carolin, Brandt, Berenice, Nikolaus, Susanna, Schäuble, Sascha, Kaleta, Christoph, Franke, Andre, Fretter, Christoph, Müller, Werner, Hütt, Marc-Thorsten, Krawczak, Michael, Schreiber, Stefan, Rosenstiel, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2017
Schlagworte:
Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749366/
https://ncbi.nlm.nih.gov/pubmed/27694142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-311651
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