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Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI

The proximal tubule epithelium relies on mitochondrial function for energy, rendering the kidney highly susceptible to ischemic AKI. Dynamin-related protein 1 (DRP1), a mediator of mitochondrial fission, regulates mitochondrial function; however, the cell-specific and temporal role of DRP1 in AKI in...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Perry, Heather M., Huang, Liping, Wilson, Rebecca J., Bajwa, Amandeep, Sesaki, Hiromi, Yan, Zhen, Rosin, Diane L., Kashatus, David F., Okusa, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748924/
https://ncbi.nlm.nih.gov/pubmed/29084809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017060659
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