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Shared cancer neoantigens: Making private matters public
In this issue of JEM, Chheda et al. (https://doi.org/10.1084/jem.20171046) report that a conserved hotspot mutation associated with an aggressive form of brain cancer generates an immunogenic T cell epitope restricted by a common HLA subtype, thereby creating a “public” neoantigen.
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| Publicado no: | J Exp Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748868/ https://ncbi.nlm.nih.gov/pubmed/29269561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172188 |
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