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Maternal IgG immune complexes induce food allergen–specific tolerance in offspring

The role of maternal immune responses in tolerance induction is poorly understood. To study whether maternal allergen sensitization affects offspring susceptibility to food allergy, we epicutaneously sensitized female mice with ovalbumin (OVA) followed by epicutaneous sensitization and oral challeng...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Ohsaki, Asa, Venturelli, Nicholas, Buccigrosso, Tess M., Osganian, Stavroula K., Lee, John, Blumberg, Richard S., Oyoshi, Michiko K.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748859/
https://ncbi.nlm.nih.gov/pubmed/29158374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171163
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