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Clinical Pharmacogenetics of Cytochrome P450-Associated Drugs in Children

Cytochrome P450 (CYP) enzymes are commonly involved in drug metabolism, and genetic variation in the genes encoding CYPs are associated with variable drug response. While genotype-guided therapy has been clinically implemented in adults, these associations are less well established for pediatric pat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pers Med
Hauptverfasser: Aka, Ida, Bernal, Christiana J., Carroll, Robert, Maxwell-Horn, Angela, Oshikoya, Kazeem A., Van Driest, Sara L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748626/
https://ncbi.nlm.nih.gov/pubmed/29099060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm7040014
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