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Landscape of Pleiotropic Proteins Causing Human Disease: Structural and System Biology Insights

Pleiotropy is the phenomenon by which the same gene can result in multiple phenotypes. Pleiotropic proteins are emerging as important contributors to rare and common disorders. Nevertheless, little is known on the mechanisms underlying pleiotropy and the characteristic of pleiotropic proteins. We an...

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Bibliographic Details
Published in:Hum Mutat
Main Authors: Ittisoponpisan, Sirawit, Alhuzimi, Eman, Sternberg, Michael J. E., David, Alessia
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748329/
https://ncbi.nlm.nih.gov/pubmed/27957775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23155
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