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CCL2, CCL5 and IGF-1 Participate in The Immunomodulation of Osteogenesis during M1/M2 Transition In Vitro

The modulation of macrophage phenotype from pro-inflammatory (M1) to tissue healing (M2) via exogenous addition of interleukin-4 (IL-4) facilitates osteogenesis; however, the molecular mediators underlying this phenomenon remain unknown. This study characterizes the IL-4-dependent paracrine crosstal...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Córdova, Luis A., Loi, Florence, Lin, Tzu-hua, Gibon, Emmanuel, Pajarinen, Jukka, Nabeshima, Akira, Lu, Laura, Yao, Zhenyu, Goodman, Stuart B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748268/
https://ncbi.nlm.nih.gov/pubmed/28782174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36166
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