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Three tRNAs on the ribosome slow translation elongation

During protein synthesis, the ribosome simultaneously binds up to three different transfer RNA (tRNA) molecules. Among the three tRNA binding sites, the regulatory role of the exit (E) site, where deacylated tRNA spontaneously dissociates from the translational complex, has remained elusive. Here we...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Choi, Junhong, Puglisi, Joseph D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748233/
https://ncbi.nlm.nih.gov/pubmed/29229848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719592115
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