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Both hyper- and hypo-activation to cognitive challenge are associated with increased beta-amyloid deposition in healthy aging: A nonlinear effect

Beta-amyloid (Aβ) positive individuals hyper-activate brain regions compared to those not at-risk; however, hyperactivation is then thought to diminish as Alzheimer’s disease symptomatology begins, evidencing eventual hypoactivation. It remains unclear when in the disease staging this transition occ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuroimage
Egile Nagusiak: Foster, Chris M., Kennedy, Kristen M., Horn, Marci M., Hoagey, David A., Rodrigue, Karen M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747976/
https://ncbi.nlm.nih.gov/pubmed/29108941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2017.10.068
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