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Structural Changes in an Anion Channelrhodopsin: Formation of the K and L Intermediates at 80 K

A recently discovered natural family of light-gated anion channelrhodopsins (ACRs) from cryptophyte algae provides an effective means of optogenetically silencing neurons. The most extensively studied ACR is from Guillardia theta (GtACR1). Earlier studies of GtACR1 have established a correlation bet...

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Publicat a:Biochemistry
Autors principals: Yi, Adrian, Li, Hai, Mamaeva, Natalia, Fernandez De Cordoba, Roberto E., Lugtenburg, Johan, DeGrip, Willem J., Spudich, John L., Rothschild, Kenneth J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747504/
https://ncbi.nlm.nih.gov/pubmed/28350445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00002
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