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Role of inflammasomes in inflammatory autoimmune rheumatic diseases

Inflammasomes are intracellular multiprotein complexes that coordinate anti-pathogenic host defense during inflammatory responses in myeloid cells, especially macrophages. Inflammasome activation leads to activation of caspase-1, resulting in the induction of pyroptosis and the secretion of pro-infl...

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Bibliographic Details
Published in:Korean J Physiol Pharmacol
Main Author: Yi, Young-Su
Format: Artigo
Language:Inglês
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746506/
https://ncbi.nlm.nih.gov/pubmed/29302207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2018.22.1.1
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