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Using single-cell multiple omics approaches to resolve tumor heterogeneity

It has become increasingly clear that both normal and cancer tissues are composed of heterogeneous populations. Genetic variation can be attributed to the downstream effects of inherited mutations, environmental factors, or inaccurately resolved errors in transcription and replication. When lesions...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Ortega, Michael A., Poirion, Olivier, Zhu, Xun, Huang, Sijia, Wolfgruber, Thomas K., Sebra, Robert, Garmire, Lana X.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746494/
https://ncbi.nlm.nih.gov/pubmed/29285690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-017-0177-y
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