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Using single-cell multiple omics approaches to resolve tumor heterogeneity

It has become increasingly clear that both normal and cancer tissues are composed of heterogeneous populations. Genetic variation can be attributed to the downstream effects of inherited mutations, environmental factors, or inaccurately resolved errors in transcription and replication. When lesions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Med
Hauptverfasser: Ortega, Michael A., Poirion, Olivier, Zhu, Xun, Huang, Sijia, Wolfgruber, Thomas K., Sebra, Robert, Garmire, Lana X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746494/
https://ncbi.nlm.nih.gov/pubmed/29285690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-017-0177-y
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