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Non-endoplasmic reticulum based calreticulin can coordinate heterocellular calcium signaling and vascular function

OBJECTIVE: In resistance arteries, endothelial cell (EC) extensions can make contact with smooth muscle cells (SMC), forming myoendothelial junctions (MEJ) at holes in the internal elastic lamina (IEL). At these holes in the IEL, calcium signaling is tightly regulated. Because calreticulin (Calr) ca...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Biwer, Lauren A, Good, Miranda E, Hong, Kwangseok, Patel, Rahul K, Agrawal, Neha, Looft-Wilson, Robin, Sonkusare, Swapnil K, Isakson, Brant E
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746467/
https://ncbi.nlm.nih.gov/pubmed/29122814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309886
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