C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways

Marsdenia tenacissimae extraction (MTE), a traditional herbal medicine, has exhibited anti-tumor effects on a variety of cancers. However, its effectiveness and the mechanism of action in Hepatocellular carcinoma (HCC) has not been fully understood. In the present study, we demonstrate that C21 ster...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Yu, Li, Kaiqiang, Ying, Youmin, Chen, Bingyu, Hao, Ke, Chen, Boxu, Zheng, Yu, Lyu, Jianxin, Tong, Xiangming, Chen, Xiaopan, Wang, Ying, Zhan, Zhajun, Zhang, Wei, Wang, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746405/
https://ncbi.nlm.nih.gov/pubmed/29299170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22833
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