Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes

To investigate the inflammatory effect of Interleukin 18 (IL-18) on rat chondrocytes and the involvement of Wnt/β-catenin and Hedgehog pathways, the mRNA and protein level of matix-degrading enzymes (MMP-2, 3, 9,13 and aggrecanses) and chondrocyte-specific proteins (Collagen II and aggrecan) were ev...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bao, Jiapeng, Ma, Chiyuan, Ran, Jisheng, Xiong, Yan, Yan, Shigui, Wu, Lidong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746357/
https://ncbi.nlm.nih.gov/pubmed/29299122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20584
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