Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

From bacteria to humans, individual cells within isogenic populations can show significant variation in stress tolerance, but the nature of this heterogeneity is not clear. To investigate this, we used single-cell RNA sequencing to quantify transcript heterogeneity in single Saccharomyces cerevisiae...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Biol
Prif Awduron: Gasch, Audrey P., Yu, Feiqiao Brian, Hose, James, Escalante, Leah E., Place, Mike, Bacher, Rhonda, Kanbar, Jad, Ciobanu, Doina, Sandor, Laura, Grigoriev, Igor V., Kendziorski, Christina, Quake, Stephen R., McClean, Megan N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746276/
https://ncbi.nlm.nih.gov/pubmed/29240790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2004050
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg