Effects of three IL-15 variants on NCI-H446 cell proliferation and expression of cell cycle regulatory molecules

Interleukin 15 (IL-15) is a cytokine exhibiting antitumor characteristic similar to that of IL-2. However, in human tissues and cells, IL-15 expression and secretion is very limited, suggesting IL-15 functions mainly intracellularly. In the present study, we assessed the effects of transfecting NCI-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ding, Jun-Ying, Wang, Zhi-Hua, Zhang, Zheng-Zheng, Cui, Xu-Ran, Hong, Yan-Ying, Liu, Qing-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746129/
https://ncbi.nlm.nih.gov/pubmed/29296227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22550
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