3-Methyladenine ameliorates liver fibrosis through autophagy regulated by the NF-κB signaling pathways on hepatic stellate cell

3-Methyladenine (3-MA) is a selective type III phosphatidylinositol 3-kinase (PI3K) inhibitor and also blocks autophagosome formation. However, the effect of 3-MA in liver fibrosis has yet to be determined. Recent studies have demonstrated that autophagy is closely related to activation of hepatic s...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wang, Bingying, Yang, Huan, Fan, Yinyin, Yang, Yong, Cao, Wei, Jia, Yanwei, Cao, Ying, Sun, Kangyun, Pang, Zhi, Du, Hong
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746093/
https://ncbi.nlm.nih.gov/pubmed/29296191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22539
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