Effect modification by region in the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced CK elevation

We investigated the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced creatine kinase (CK) elevation among Chinese patients with hyperlipidemia. A total of587 enrolled individuals were treated with 20 mg/d oral simvastatin for 8 consecutive weeks. Genotyping of LEP G2548A a...

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Pubblicato in:Oncotarget
Autori principali: Jiang, Shanqun, Venners, Scott A., Li, Kang, Hsu, Yi-Hsiang, Weinstock, Justin, Zou, Yanfeng, Pan, Faming, Xu, Xiping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746089/
https://ncbi.nlm.nih.gov/pubmed/29296187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22506
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