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Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles

In many asymmetrically dividing cells, the microtubule-organizing centers (MTOCs; mammalian centrosome and yeast spindle pole body [SPB]) nucleate more astral microtubules on one of the two spindle poles than the other. This differential activity generally correlates with the age of MTOCs and contri...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Lengefeld, Jette, Yen, Eric, Chen, Xiuzhen, Leary, Allen, Vogel, Jackie, Barral, Yves
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746063/
https://ncbi.nlm.nih.gov/pubmed/29142076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0725
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