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Dysregulation of NRF2 in Cancer: from Molecular Mechanisms to Therapeutic Opportunities
Nuclear factor E2-related factor 2 (NRF2) plays an important role in redox metabolism and antioxidant defense. Under normal conditions, NRF2 proteins are maintained at very low levels because of their ubiquitination and proteasomal degradation via binding to the kelch-like ECH associated protein 1 (...
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| Vydáno v: | Biomol Ther (Seoul) |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Korean Society of Applied Pharmacology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746038/ https://ncbi.nlm.nih.gov/pubmed/29212307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2017.195 |
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