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Melanosomal Damage in Normal Human Melanocytes Induced by UVB and Metal Uptake-A Basis for the Pro-oxidant State of Melanoma()

Melanins are ubiquitous catecholic pigments, formed in organelles called melanosomes within melanocytes, the function of which is to protect skin against harmful effects of UV radiation. Melanosomes within melanoma cells are characteristically abnormal, with fragmented melanin and disrupted membrane...

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Detalhes bibliográficos
Publicado no:Photochem Photobiol
Main Authors: Gidanian, Shirley, Mentelle, Mallory, Meyskens, Frank L., Farmer, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746029/
https://ncbi.nlm.nih.gov/pubmed/18331399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2008.00309.x
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