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Novel methods for genotype imputation to whole-genome sequence and a simple linear model to predict imputation accuracy

BACKGROUND: Accurate imputation plays a major role in genomic studies of livestock industries, where the number of genotyped or sequenced animals is limited by costs. This study explored methods to create an ideal reference population for imputation to Next Generation Sequencing data in cattle. METH...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Larmer, Steven G., Sargolzaei, Mehdi, Brito, Luiz F., Ventura, Ricardo V., Schenkel, Flávio S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746022/
https://ncbi.nlm.nih.gov/pubmed/29281958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-017-0588-1
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