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Expitope 2.0: a tool to assess immunotherapeutic antigens for their potential cross-reactivity against naturally expressed proteins in human tissues

BACKGROUND: Adoptive immunotherapy offers great potential for treating many types of cancer but its clinical application is hampered by cross-reactive T cell responses in healthy human tissues, representing serious safety risks for patients. We previously developed a computational tool called Expito...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Jaravine, Victor, Mösch, Anja, Raffegerst, Silke, Schendel, Dolores J., Frishman, Dmitrij
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745885/
https://ncbi.nlm.nih.gov/pubmed/29282079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3854-8
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