Hepatitis C and Alcohol Exacerbate Liver Injury by Suppression of FOXO3

Hepatitis C virus (HCV) infection exacerbates alcoholic liver injury by mechanisms that include enhanced oxidative stress. The forkhead box transcription factor FOXO3 is an important component of the antioxidant stress response that can be altered by HCV. To test whether FOXO3 is protective for alco...

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Publicado en:Am J Pathol
Autores principales: Tumurbaatar, Batbayar, Tikhanovich, Irina, Li, Zhuan, Ren, Jinyu, Ralston, Robert, Kuravi, Sudhakiranmayi, Campbell, Roosevelt, Chaturvedi, Gaurav, Huang, Ting-Ting, Zhao, Jie, Hao, Junfang, O’Neil, Maura, Weinman, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745546/
https://ncbi.nlm.nih.gov/pubmed/24225087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.08.013
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