Whole-Genome Methylation Sequencing Reveals Distinct Impact of Differential Methylations on Gene Transcription in Prostate Cancer

DNA methylation is one of the most important epigenetic mechanisms in regulating gene expression. Genome hypermethylation has been proposed as a critical mechanism in human malignancies. However, whole-genome quantification of DNA methylation of human malignancies has rarely been investigated, and t...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Principais autores: Yu, Yan P., Ding, Ying, Chen, Rui, Liao, Serena G., Ren, Bao-Guo, Michalopoulos, Amantha, Michalopoulos, George, Nelson, Joel, Tseng, George C., Luo, Jian-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745540/
https://ncbi.nlm.nih.gov/pubmed/24113458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.08.018
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