Altered GluA1 function and accumbal synaptic plasticity in the ClockΔ19 model of bipolar mania

BACKGROUND: Disruptions in circadian rhythms are associated with an increased risk for bipolar disorder (BD). Moreover, studies show that the circadian protein CLOCK is involved in regulating monoaminergic systems and mood-related behavior. However the molecular and synaptic mechanisms underlying th...

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Pubblicato in:Biol Psychiatry
Autori principali: Parekh, Puja K., Becker-Krail, Darius, Sundaravelu, Poornima, Ishigaki, Shinsuke, Okado, Haruo, Sobue, Gen, Huang, Yanhua, McClung, Colleen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745309/
https://ncbi.nlm.nih.gov/pubmed/28780133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.06.022
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