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Targeting the Wnt/beta-catenin Pathway in Cancer: Update on Effectors and Inhibitors

The Wnt/beta-catenin pathway is a family of proteins that is implicated in many vital cellular functions like stem cell regeneration and organogenesis. Several intra-cellular signal transduction pathways are induced by Wnt, notably the Wnt/beta-catenin dependent pathway or canonical pathway and the...

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Detalhes bibliográficos
Publicado no:Cancer Treat Rev
Main Authors: Krishnamurthy, Nithya, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745276/
https://ncbi.nlm.nih.gov/pubmed/29169144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2017.11.002
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