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The m.7510T>C mutation: Hearing impairment and a complex neurologic phenotype

OBJECTIVES: Mutations in mitochondrial DNA cause a variety of clinical phenotypes ranging from a mild hearing impairment (HI) to severe encephalomyopathy. The MT‐TS1 gene is a hotspot for mutations causing HI. The m.7510T>C mutation in MT‐TS1 has been previously associated with non‐syndromic HI i...

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Dades bibliogràfiques
Publicat a:Brain Behav
Autors principals: Kytövuori, Laura, Gardberg, Maria, Majamaa, Kari, Martikainen, Mika H.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745241/
https://ncbi.nlm.nih.gov/pubmed/29299381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.859
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