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Shigella entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation

Disruption of the sumoylation/desumoylation equilibrium is associated with several disease states such as cancer and infections, however the mechanisms regulating the global SUMO balance remain poorly defined. Here, we show that infection by Shigella flexneri, the causative agent of human bacillary...

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書目詳細資料
發表在:eLife
Main Authors: Lapaquette, Pierre, Fritah, Sabrina, Lhocine, Nouara, Andrieux, Alexandra, Nigro, Giulia, Mounier, Joëlle, Sansonetti, Philippe, Dejean, Anne
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745084/
https://ncbi.nlm.nih.gov/pubmed/29231810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27444
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