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APOL1 renal risk variants: Fertile soil for HIV-associated nephropathy

Apolipoprotein L1 (APOL1) genetic variants are potent risk factors for glomerular disease, but one or more additional factors are required for expression of glomerular disease. Uncontrolled or poorly controlled HIV infection is the most potent susceptibility factor for APOL1 nephropathy that has bee...

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Bibliographic Details
Published in:Semin Nephrol
Main Authors: Kopp, Jeffrey B., Heymann, Jurgen, Winkler, Cheryl A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745063/
https://ncbi.nlm.nih.gov/pubmed/29110758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2017.07.004
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