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Association of FLG single nucleotide variations with clinical phenotypes of atopic dermatitis

BACKGROUND: FLG encodes a large protein called profilaggrin, which plays a key role in maintaining an effective skin barrier against the environment. In this study, we identified FLG single nucleotide variations (FLG-SNVs) and evaluated the association of FLG-SNVs with clinical phenotypes including...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Myungshin, Yoo, Jaeeun, Kim, Jiyeon, Park, Joonhong, Han, Eunhee, Jang, Woori, Chae, Hyojin, Lee, Ji Hyun, Park, Young Min, Kim, Yonggoo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744964/
https://ncbi.nlm.nih.gov/pubmed/29281699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190077
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