Candida albicans-derived mannoproteins activate NF-κB in reporter cells expressing TLR4, MD2 and CD14

The ability of soluble C. albicans 20A (serotype A) mannoprotein (CMP) to serve as a ligand for toll-like receptor 4 (TLR4) and its co-receptors was examined using commercially available and stably-transfected HEK293 cells that express human TLR4, MD2 and CD14, but not MR. These TLR4 reporter cells...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ness, Traci, Abdallah, Mahmud, Adams, Jaime, Alvarado, Claudia, Gunn, Edwin, House, Brittany, Lamb, John, Macguire, Jack, Norris, Emily, Robinson, Rebekah, Sapp, Morgan, Sharma, Jill, Garner, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744952/
https://ncbi.nlm.nih.gov/pubmed/29281684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189939
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