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Parkinsonism without dopamine neuron degeneration in aged DOPA-responsive dystonia knockin mice
BACKGROUND: Recent neuroimaging studies implicate nigrostriatal degeneration as a critical factor in producing late-onset parkinsonism in patients with DRD-causing mutations. However, postmortem anatomical studies do not reveal neurodegeneration in DRD patients. These contrasting findings make it un...
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| 發表在: | Mov Disord |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5744486/ https://ncbi.nlm.nih.gov/pubmed/28949038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27169 |
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