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AvaR1, a Butenolide-Type Autoregulator Receptor in Streptomyces avermitilis, Directly Represses Avenolide and Avermectin Biosynthesis and Multiple Physiological Responses

Avermectins are commercially important anthelmintic antibiotics produced by Streptomyces avermitilis. The homologous TetR-family transcriptional regulators AvaR1 and AvaR2 in this species were identified previously as receptors of avenolide, a novel butenolide-type autoregulator signal required for...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Zhu, Jianya, Chen, Zhi, Li, Jilun, Wen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744401/
https://ncbi.nlm.nih.gov/pubmed/29312254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02577
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