Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients

BACKGROUND: Enterococcus faecium is a leading cause of hospital-acquired infection, particularly in the immunocompromised. Here, we use whole genome sequencing of E. faecium to study within-host evolution and the transition from gut carriage to invasive disease. METHODS: We isolated and sequenced 18...

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Dettagli Bibliografici
Pubblicato in:Genome Med
Autori principali: Moradigaravand, Danesh, Gouliouris, Theodore, Blane, Beth, Naydenova, Plamena, Ludden, Catherine, Crawley, Charles, Brown, Nicholas M., Török, M. Estée, Parkhill, Julian, Peacock, Sharon J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744393/
https://ncbi.nlm.nih.gov/pubmed/29282103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0507-0
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