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Multiple Phenotype Association Tests Using Summary Statistics in Genome-Wide Association Studies

We study in this paper jointly testing the associations of a genetic variant with correlated multiple phenotypes using the summary statistics of individual phenotype analysis from Genome-Wide Association Studies (GWASs). We estimated the between-phenotype correlation matrix using the summary statist...

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Detalhes bibliográficos
Publicado no:Biometrics
Main Authors: Liu, Zhonghua, Lin, Xihong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743780/
https://ncbi.nlm.nih.gov/pubmed/28653391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12735
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