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Liposomal Cytarabine Induces Less Neurocognitive Dysfunction than Intrathecal Methotrexate in an Animal Model

Liposomal cytarabine is currently being tested clinically as an alternative to intrathecal (IT) methotrexate (MTX) for preventing relapse within the central nervous system among patients with acute lymphoblastic leukemia (ALL). To compare the toxicity and cognitive deficits caused by IT MTX versus l...

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Detalhes bibliográficos
Publicado no:J Pediatr Hematol Oncol
Main Authors: Thomsen, Anna Maja, Gulinello, Maria E., Wen, Jing, Schmiegelow, Kjeld, Cole, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743776/
https://ncbi.nlm.nih.gov/pubmed/28654460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000888
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