CP-25, a Novel Anti-inflammatory and Immunomodulatory Drug, Inhibits the Functions of Activated Human B Cells through Regulating BAFF and TNF-alpha Signaling and Comparative Efficacy with Biological Agents

Paeoniflorin-6′-O-benzene sulfonate (code: CP-25) was the chemistry structural modifications of Paeoniflorin (Pae). CP-25 inhibited B cells proliferation stimulated by B cell activating factor belonging to the TNF family (BAFF) or Tumor necrosis factor alpha (TNF-alpha). CP-25, Rituximab and Etanerc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Zhang, Feng, Shu, Jin-Ling, Li, Ying, Wu, Yu-Jing, Zhang, Xian-Zheng, Han, Le, Tang, Xiao-Yu, Wang, Chen, Wang, Qing-Tong, Chen, Jing-Yu, Chang, Yan, Wu, Hua-Xun, Zhang, Ling-Ling, Wei, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2017
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743740/
https://ncbi.nlm.nih.gov/pubmed/29311935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00933
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