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Genetic screening in two Iranian families with early onset Alzheimer’s disease identified a novel PSEN1 mutation

A subset of early onset Alzheimer’s disease (AD) is inherited as an autosomal dominant trait and is associated with mutations in the genes encoding β-amyloid precursor protein, presenilin 1, or presenilin 2. In this study, we identified two PSEN1 mutations (one novel and one known) in two unrelated...

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Библиографические подробности
Опубликовано в: :Neurobiol Aging
Главные авторы: Wang, Jen-Chyong, Alinaghia, Somayeh, Tafakhori, Abbas, Sikora, Elizabeth, Azcona, Luis J., Karkheiran, Siamak, Goate, Alison, Paisán-Ruiz, Coro, Darvish, Hossein
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743634/
https://ncbi.nlm.nih.gov/pubmed/29175279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.10.011
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