Tumor-penetrating Peptide Conjugated and Doxorubicin Loaded T(1)-T(2) Dual Mode MRI Contrast Agents Nanoparticles for Tumor Theranostics

The conventional chemotherapeutics could not be traced in vivo and provide timely feedback on the clinical effectiveness of drugs. Methods: In this study, a tumor-penetrating peptide RGERPPR (RGE) modified, Gd-DTPA conjugated, and doxorubicin (DOX) loaded Fe(3)O(4)@SiO(2)@mSiO(2) nanoparticle drug d...

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Bibliographic Details
Published in:Theranostics
Main Authors: Gao, Lipeng, Yu, Jing, Liu, Yang, Zhou, Jinge, Sun, Lei, Wang, Jing, Zhu, Jianzhong, Peng, Hui, Lu, Weiyue, Yu, Lei, Yan, Zhiqiang, Wang, Yiting
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743462/
https://ncbi.nlm.nih.gov/pubmed/29290795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21074
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