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European perspective on the management of rheumatoid arthritis: clinical utility of tofacitinib

Xeljanz(®) (tofacitinib) is an oral small-molecule inhibitor that reversibly inhibits Janus-activated kinase (JAK)-dependent cytokine signaling, thus reducing inflammation. As a result of these mechanisms, effects on the immune system such as a moderate decrease in the total lymphocyte count, a dose...

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Detalhes bibliográficos
Publicado no:Ther Clin Risk Manag
Main Authors: Kawalec, Paweł, Śladowska, Katarzyna, Malinowska-Lipień, Iwona, Brzostek, Tomasz, Kózka, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743127/
https://ncbi.nlm.nih.gov/pubmed/29317823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S138677
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