Traumatic osteoarthritis-induced persistent mechanical hyperalgesia in a rat model of anterior cruciate ligament transection plus a medial meniscectomy

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage degeneration, subchondral bone changes, osteophyte formation, and synovitis. A major symptom is pain that is triggered by peripheral and central changes within the pain pathways. Some surgery-induc...

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Bibliographic Details
Published in:J Pain Res
Main Authors: Tsai, Hsiao-Chien, Chen, Ta-Liang, Chen, Yu-Pin, Chen, Ruei-Ming
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743113/
https://ncbi.nlm.nih.gov/pubmed/29317848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S154038
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