Ablation of the riboflavin-binding protein retbindin reduces flavin levels and leads to progressive and dose-dependent degeneration of rods and cones

The interface between the neural retina and the retinal pigment epithelium (RPE) is critical for several processes, including visual pigment regeneration and retinal attachment to the RPE. One of its most important functions is the exchange of metabolites between the photoreceptors and RPE because p...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Kelley, Ryan A., Al-Ubaidi, Muayyad R., Sinha, Tirthankar, Genc, Ayse M., Makia, Mustafa S., Ikelle, Larissa, Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743076/
https://ncbi.nlm.nih.gov/pubmed/29079576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785105
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