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Potential role of the methylation of VEGF gene promoter in response to hypoxia in oxygen‐induced retinopathy: beneficial effect of the absence of AQP4

Hypoxia‐dependent accumulation of vascular endothelial growth factor (VEGF) plays a major role in retinal diseases characterized by neovessel formation. In this study, we investigated whether the glial water channel Aquaporin‐4 (AQP4) is involved in the hypoxia‐dependent VEGF upregulation in the ret...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Pisani, Francesco, Cammalleri, Maurizio, Dal Monte, Massimo, Locri, Filippo, Mola, Maria Grazia, Nicchia, Grazia Paola, Frigeri, Antonio, Bagnoli, Paola, Svelto, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742711/
https://ncbi.nlm.nih.gov/pubmed/28940930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13348
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