Adiponectin attenuates profibrotic extracellular matrix remodeling following cardiac injury by up‐regulating matrix metalloproteinase 9 expression in mice

Adiponectin (APN) is a multifunctional adipocytokine that inhibits myocardial fibrosis, dilatation, and left ventricular (LV) dysfunction after myocardial infarction (MI). Coxsackievirus B3 (CVB3) myocarditis is associated with intense extracellular matrix (ECM) remodeling which might progress to di...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Jenke, Alexander, Schur, Robert, Röger, Carsten, Karadeniz, Zehra, Grüger, Mathias, Holzhauser, Luise, Savvatis, Kostas, Poller, Wolfgang, Schultheiss, Heinz‐Peter, Landmesser, Ulf, Skurk, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742698/
https://ncbi.nlm.nih.gov/pubmed/29263115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13523
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