Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extra-oral halitosis

Selenium binding protein1 (SELENBP1) has been associated with several cancers. Its exact role was unknown. We show that SELENBP1 is a methanethiol oxidase (MTO), related to MTO of methylotrophic bacteria, converting methanethiol to H(2)O(2), formaldehyde and H(2)S, an activity not known to exist in...

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Publicado no:Nat Genet
Main Authors: Pol, Arjan, Renkema, G. Herma, Tangerman, Albert, Winkel, Edwin G., Engelke, Udo F., de Brouwer, Arjan P. M., Lloyd, Kent C., Araiza, Renee S., van den Heuvel, Lambert, Omran, Heymut, Olbrich, Heike, Elberink, Marijn Oude, Gilissen, Christian, Rodenburg, Richard J., Sass, Jörn Oliver, Schwab, K. Otfried, Schäfer, Hendrik, Venselaar, Hanka, Sequeira, J. Silvia, Op den Camp, Huub J.M., Wevers, Ron A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742538/
https://ncbi.nlm.nih.gov/pubmed/29255262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-017-0006-7
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