Impact of tissue transport on PET hypoxia quantification in pancreatic tumours

BACKGROUND: The clinical impact of hypoxia in solid tumours is indisputable and yet questions about the sensitivity of hypoxia-PET imaging have impeded its uptake into routine clinical practice. Notably, the binding rate of hypoxia-sensitive PET tracers is slow, comparable to the rate of diffusive e...

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Pubblicato in:EJNMMI Res
Autori principali: Taylor, Edward, Gottwald, Jennifer, Yeung, Ivan, Keller, Harald, Milosevic, Michael, Dhani, Neesha C., Siddiqui, Iram, Hedley, David W., Jaffray, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2017
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741574/
https://ncbi.nlm.nih.gov/pubmed/29273939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0347-3
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